In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity
Ningqiang Gong, Xuexiang Han, Lulu Xue, Rakan El‐Mayta, Ann E. Metzloff, Margaret M. Billingsley, Alex G. Hamilton, Michael J. Mitchell
Topics & Concepts
Cytokine release syndromePEGylationIn situNeurotoxicityCytokineChemistryMaterials scienceImmunologyMedicineChimeric antigen receptorBiochemistryT cellImmune systemToxicityOrganic chemistryPolyethylene glycolCAR-T cell therapy researchNanowire Synthesis and ApplicationsImmune Cell Function and Interaction