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Direct and efficient synthesis of tetrasubstituted allenyl organothiophosphates from propargylic alcohols under catalyst- and additive-free conditions

Yuxing Zhang, Sha Du, Tao Yang, Fengyan Jin, Jingyi Zhou, Banpeng Cao, Zhijie Mao, Xian‐Rong Song, Qiang Xiao

2022Organic Chemistry Frontiers18 citationsDOI

Abstract

An environment-friendly approach that affords tetrasubstituted allenyl organothiophosphates from easily prepared propargylic alcohols and phosphorothioic acids [(RO) 2 P(O)SH] with water as the only by-product is developed.

Topics & Concepts

ChemistryCatalysisCombinatorial chemistryOrganic chemistryCatalytic Alkyne ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods
Direct and efficient synthesis of tetrasubstituted allenyl organothiophosphates from propargylic alcohols under catalyst- and additive-free conditions | Litcius