New isatin-chitosan Schiff base hybrids: Tri-functional bioactives for antimicrobial, anticancer, and antioxidant therapies supported by in silico docking and ADMET studies
Mohamed A. Ragheb, Mostafa E. Salem, Amira A Hamed, Ismail A. Abdelhamid, Hossameldin A. Ali, Mohamed Abdel‐Megid, Ahmed M. Elgamal
Topics & Concepts
In silicoChemistryDocking (animal)DruggabilityDNA gyraseAntibacterial activityBiochemistryAntioxidantTopoisomeraseDPPHEscherichia coliEnterococcus faecalisDNA damageStaphylococcus aureusCombinatorial chemistryHep G2Schiff baseStructure–activity relationshipBiological activityMechanism of actionAntibacterial agentCell growthQuantitative structure–activity relationshipCell cycleDNACell cycle checkpointTopoisomerase IVPharmacologyCellPolyphenolNanocomposite Films for Food PackagingAdvanced Drug Delivery Systemsbiodegradable polymer synthesis and properties