In vivo generation of anti-BCMA CAR-T cells in relapsed or refractory multiple myeloma: a phase 1 study
Ning An, Da‐Zhi Wang, Peiling Zhang, Jishuai Zhang, Philippe A. Parone, Jianlin Hu, Yuhan Bao, Li Xu, Haitao Ruan, Ying Wan, Xin Wen, Yi Gao, Chunrui Li
Topics & Concepts
TolerabilityMedicineCytokine release syndromeIn vivoEx vivoPharmacokineticsAdverse effectClinical endpointClinical trialPharmacodynamicsPharmacologyRefractory (planetary science)Internal medicinePhases of clinical researchOncologyToxicityImmunotherapyChimeric antigen receptorGastroenterologyT cellImmune systemMinimal residual diseaseImmunologyAntigenDrugTransplantationCytokineSurgerySurrogate endpointMethotrexateProgressive diseaseAldesleukinCAR-T cell therapy researchImmunotherapy and Immune ResponsesVirus-based gene therapy research