P(III)/P(V)-Catalyzed Methylamination of Arylboronic Acids and Esters: Reductive C–N Coupling with Nitromethane as a Methylamine Surrogate
Gen Li, Ziyang Qin, Alexander T. Radosevich
Abstract
), revealing this easy-to-handle compound as a versatile precursor for the direct installation of the methylamino group.
Topics & Concepts
ChemistryNitromethaneMethylamineCatalysisCombinatorial chemistryReductive eliminationMedicinal chemistryOrganic chemistryChemical Reactions and IsotopesAsymmetric Hydrogenation and CatalysisCatalytic Cross-Coupling Reactions