Ultra-small lipid nanoparticles encapsulating sorafenib and midkine-siRNA selectively-eradicate sorafenib-resistant hepatocellular carcinoma in vivo
Mahmoud A. Younis, Ikramy A. Khalil, Yaser Hosny Ali Elewa, Yasuhiro Kon, Hideyoshi Harashima
Topics & Concepts
SorafenibIn vivoHepatocellular carcinomaCancer researchPharmacologyGene silencingChemistryMidkineLiver cancerMedicineBiologyBiochemistryGrowth factorBiotechnologyGeneReceptorRNA Interference and Gene DeliveryGlycosylation and Glycoproteins ResearchHepatocellular Carcinoma Treatment and Prognosis