FAK inhibitor PF-562271 inhibits the migration and proliferation of high-grade serous ovarian cancer cells through FAK and FAK mediated cell cycle arrest
Qionghui Pan, Qingyu Wang, Tianshu Zhao, Xinyu Zhao, Yixin Liang, Mengyun Shi, Cong Chen, Feng Lin
Topics & Concepts
Focal adhesionCancer researchCell cycleCell growthCell cycle checkpointCell migrationG1 phaseChemistryCell biologyCellSignal transductionBiologyBiochemistryCell Adhesion Molecules ResearchCellular Mechanics and InteractionsProtease and Inhibitor Mechanisms