Synthetic biology strategies for cyanobacterial systems to heterologously produce cyanobacterial natural products
Manyun Chen, Dipesh Dhakal, Campbell W. Eckhardt, Hendrik Luesch, Yousong Ding
Abstract
sp. PCC 7120, and emerging hosts. Advances in BGC cloning, combinatorial biosynthesis, transcriptional and translational regulation, and host engineering are also highlighted. Together, these synthetic biology developments provide a powerful framework for expanding cyanobacterial natural product discovery and production.
Topics & Concepts
Synthetic biologyNatural productNatural (archaeology)BiologyHeterologousCyanobacteriaComputational biologyKey (lock)Biochemical engineeringBiotechnologyEcologyBacteriaGeneticsEngineeringGeneBiochemistryPaleontologyAlgal biology and biofuel productionPhotosynthetic Processes and MechanismsMicrobial Community Ecology and Physiology