FBXW7 regulates the sensitivity of imatinib in gastrointestinal stromal tumors by targeting MCL1
Xiyu Wu, Masaaki Iwatsuki, Masakazu Takaki, Takuro Saito, Tsutomu Hayashi, Masato Kondo, Yoshiharu Sakai, Naoto Gotohda, Eiji Tanaka, Toshirou Nishida, Hideo Baba
Topics & Concepts
ImatinibGiSTMedicineMCL1Cancer researchImatinib mesylateIn vivoOncologyInternal medicineApoptosisStromal cellPharmacologyBiologyDownregulation and upregulationGeneMyeloid leukemiaBiotechnologyBiochemistryGastrointestinal Tumor Research and TreatmentChronic Myeloid Leukemia TreatmentsChromatin Remodeling and Cancer