Multistate Redox-Switchable Ion Transport Using Chalcogen-Bonding Anionophores
Andrew Docker, Toby G. Johnson, Heike Kuhn, Zongyao Zhang, Matthew J. Langton
Abstract
High Resolution Image Download MS PowerPoint Slide Synthetic supramolecular transmembrane anionophores have emerged as promising anticancer chemotherapeutics. However, key to their targeted application is achieving spatiotemporally controlled activity. Herein, we report a series of chalcogen-bonding diaryl tellurium-based transporters in which their anion binding potency and anionophoric activity are controlled through reversible redox cycling between Te oxidation states. This unprecedented in situ reversible multistate switching allows for switching between ON and OFF anion transport and is crucially achieved with biomimetic chemical redox couples.
Topics & Concepts
ChemistryChalcogenRedoxIonNanotechnologyInorganic chemistryCrystallographyOrganic chemistryMaterials scienceMolecular Sensors and Ion DetectionElectrochemical Analysis and ApplicationsSupramolecular Chemistry and Complexes