Nonlinear response to cancer nanotherapy due to macrophage interactions revealed by mathematical modeling and evaluated in a murine model via CRISPR-modulated macrophage polarization
Fransisca Leonard, Louis T. Curtis, Ahmed R. Hamed, Carolyn Zhang, Eric Chau, Devon Sieving, Biana Godin, Hermann B. Frieboes
Topics & Concepts
Macrophage polarizationMacrophageCancer researchPopulationImmune systemM2 MacrophageIn vitroMedicineImmunologyBiologyBiochemistryEnvironmental healthImmune cells in cancerReproductive System and PregnancyCancer Cells and Metastasis