Fraxin (7-hydroxy-6-methoxycoumarin 8-glucoside) confers protection against ionizing radiation-induced intestinal epithelial injury in vitro and in vivo
Feng‐Ling Tang, Liwei Xie, Linfeng Tang, Haiyan Lu, Ruiqiu Zhu, Difan Wang, Ye Tian, Shang Cai, Ming Li
Topics & Concepts
In vivoOxidative stressIntestinal epitheliumEx vivoPharmacologyPopulationIonizing radiationLGR5Downregulation and upregulationIntestinal mucosaInterleukin 22BiologyBarrier functionInflammationCancer researchMedicineImmunologyStem cellCytokineCell biologyEpitheliumPathologyInternal medicineInterleukinBiochemistryCancer stem cellIrradiationPhysicsNuclear physicsEnvironmental healthBiotechnologyGeneEffects of Radiation ExposureOral health in cancer treatmentCancer Cells and Metastasis