Regio/site-selective alkylation of substrates containing a <i>cis</i>-, 1,2- or 1,3-diol with ferric chloride and dipivaloylmethane as the catalytic system
Jian Lv, Yu Liu, Jiajia Zhu, Dapeng Zou, Hai Dong
Abstract
We reported the regio/site-selective alkylation of diols and polyols with FeCl<sub>3</sub> as a key catalyst and confirmed the mechanism.
Topics & Concepts
AlkylationChlorideFerricCatalysisChemistryDiolOrganic chemistryMedicinal chemistryCombinatorial chemistryFluorine in Organic ChemistryAsymmetric Synthesis and CatalysisSynthetic Organic Chemistry Methods