Simultaneous detection of phenacetin and paracetamol using ELISA and a gold nanoparticle-based immunochromatographic test strip
Jingjing Yao, Xinxin Xu, Liqiang Liu, Hua Kuang, Zhengyou Wang, Chuanlai Xu
Abstract
ELISA and GNP-ICS assays were applied to determine PNCT-spiked beverage samples without pretreatment, in addition to a kind of PAP-containing drug. The recoveries were validated using high performance liquid chromatography (HPLC). The results revealed that the developed GNP-ICS assay was reliable for the detection of PNCT in practical samples.
Topics & Concepts
ChromatographyDetection limitChemistryPhenacetinHigh-performance liquid chromatographyColloidal goldMonoclonal antibodyNanoparticleAntibodyMaterials scienceNanotechnologyMedicineImmunologyAdvanced biosensing and bioanalysis techniquesElectrochemical sensors and biosensorsDrug-Induced Adverse Reactions