Litcius/Paper detail

EasyVS: a user-friendly web-based tool for molecule library selection and structure-based virtual screening

Douglas E. V. Pires, Wandré Nunes de Pinho Veloso, Yoochan Myung, Carlos H. M. Rodrigues, Michael Silk, Pâmela Marinho Rezende, Francislon Silva, Joicymara S. Xavier, João Paulo Linhares Velloso, Carlos Henrique da Silveira, David B. Ascher

2020Bioinformatics32 citationsDOIOpen Access PDF

Abstract

SUMMARY: EasyVS is a web-based platform built to simplify molecule library selection and virtual screening. With an intuitive interface, the tool allows users to go from selecting a protein target with a known structure and tailoring a purchasable molecule library to performing and visualizing docking in a few clicks. Our system also allows users to filter screening libraries based on molecule properties, cluster molecules by similarity and personalize docking parameters. AVAILABILITY AND IMPLEMENTATION: EasyVS is freely available as an easy-to-use web interface at http://biosig.unimelb.edu.au/easyvs. CONTACT: [email protected] or [email protected]. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Topics & Concepts

Selection (genetic algorithm)User FriendlyComputer scienceVirtual screeningWeb siteWorld Wide WebThe InternetBioinformaticsArtificial intelligenceOperating systemBiologyDrug discoveryComputational Drug Discovery MethodsProtein Structure and DynamicsChemical Synthesis and Analysis