Testosterone attenuates hypoxia-induced hypertension by affecting NRF1-mediated transcriptional regulation of ET-1 and ACE
Shan Jiang, Guijuan Chen, Zhihui Yang, Dan Wang, Yapeng Lu, Li Zhu, Xueting Wang
Topics & Concepts
NRF1EndocrinologyHypoxia (environmental)Internal medicineDownregulation and upregulationEndothelial dysfunctionAngiotensin-converting enzyme 2Angiotensin IIChemistryBiologyBlood pressureMedicineTranscription factorBiochemistryOxygenGeneDiseaseOrganic chemistryInfectious disease (medical specialty)Coronavirus disease 2019 (COVID-19)Eicosanoids and Hypertension PharmacologyHigh Altitude and HypoxiaAdipose Tissue and Metabolism