Targeting the senescence-associated secretory phenotype to modify osteoarthritis in aging
Muhammad Afzal, M. M. Rekha, Samir Sahoo, Surya Nath Pandey, C. Maji, Kavita Goyal, Haider Ali, Sachin Kumar Singh, Gaurav Gupta, Md Sadique Hussain
Topics & Concepts
OsteoarthritisChondrocytePhenotypeEpigeneticsArticular cartilageCartilageAutophagyMedicineBioinformaticsOxidative stressExtracellular vesiclesPathologicalBiologyImmunologyCell biologySynovial jointFunction (biology)Degeneration (medical)SecretionArticular cartilage damageInflammationNeuroscienceSubchondral boneMitochondrionExosomeExtracellular vesicleExtracellular matrixRheumatologyExtracellularPathologyDiseasemicroRNAJoint (building)Telomeres, Telomerase, and SenescenceImmune Response and InflammationPsoriasis: Treatment and Pathogenesis