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Understanding the Impact of Menopause on Women With Schizophrenia-Spectrum Disorders: A Comprehensive Review

Swasti Tiwari, Roshan Prasad, Mayur Wanjari, Ranjana Sharma

2023Cureus16 citationsDOIOpen Access PDF

Abstract

Menopause is a physiological event in women's lives that typically transpires in midlife, denoting the cessation of ovarian function and ultimately leading to the end of reproductive capacity. However, women with schizophrenia-spectrum disorders may encounter unique challenges during this period because of the interaction between hormonal changes and their pre-existing mental health conditions. This literature review aims to investigate the consequences of menopause on women with schizophrenia-spectrum disorders, including modifications in symptomatology, cognitive function, and quality of life. Potential interventions will also be examined, including hormone replacement therapy and psychosocial support. The study findings suggest that menopause can worsen symptoms, such as hallucinations and delusions, and may also impair cognitive function, resulting in memory and executive function difficulties. Nevertheless, hormone replacement therapy and psychosocial support could offer potential avenues to manage symptoms and improve the quality of life for women with schizophrenia-spectrum disorders during menopause.

Topics & Concepts

MenopauseMedicinePsychosocialSchizophrenia (object-oriented programming)Quality of life (healthcare)Psychological interventionCognitionPsychiatryHormone replacement therapy (female-to-male)Clinical psychologyEndocrinologyTestosterone (patch)NursingMenopause: Health Impacts and TreatmentsEndometriosis Research and TreatmentEstrogen and related hormone effects