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Mesenchymal stem cell-derived extracellular vesicles prevent glioma by blocking M2 polarization of macrophages through a miR-744-5p/TGFB1-dependent mechanism

Ling Liu, Meixiong Cheng, Tian Zhang, Yong Chen, Yaqiu Wu, Qi Wang

2022Cell Biology and Toxicology48 citationsDOI

Topics & Concepts

GliomaMesenchymal stem cellMacrophage polarizationCancer researchMAPK/ERK pathwayM2 MacrophageCell biologyChemistryBiologySignal transductionMacrophageIn vitroBiochemistryExtracellular vesicles in diseaseImmune cells in cancerGlioma Diagnosis and Treatment
Mesenchymal stem cell-derived extracellular vesicles prevent glioma by blocking M2 polarization of macrophages through a miR-744-5p/TGFB1-dependent mechanism | Litcius