Dihydrosanguinarine based RNA-seq approach couple with network pharmacology attenuates LPS-induced inflammation through TNF/IL-17/PI3K/AKT pathways in mice liver
Yan Xiang, Hao Zhang, Zheng Xu Zhang, Xiao Yang Qu, Fen Xia Zhu
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwaySignal transductionInflammationPharmacologyTumor necrosis factor alphaCXCL1BiologyProinflammatory cytokineTranscriptomeChemistryChemokineCancer researchCell biologyImmunologyGene expressionBiochemistryGeneComputational Drug Discovery MethodsBerberine and alkaloids researchMicroRNA in disease regulation