Effect of P-glycoprotein Inhibition on the Penetration of Ceftriaxone Across the Blood–Brain Barrier
Yuheng Shan, Yuying Cen, Yan‐Jin Zhang, Ruishu Tan, Jiahua Zhao, Zhiyong Nie, Jiatang Zhang, Shengyuan Yu
Topics & Concepts
VerapamilP-glycoproteinBlood–brain barrierPharmacologyMicrodialysisEffluxTransporterPenetration (warfare)ChemistryPharmacokineticsMedicineCentral nervous systemInternal medicineBiochemistryAntibioticsMultiple drug resistanceGeneCalciumEngineeringOperations researchDrug Transport and Resistance MechanismsAntibiotics Pharmacokinetics and EfficacyEpilepsy research and treatment