Litcius/Paper detail

Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection

Cason R. King, Yiping Liu, Katherine A. Amato, Grace A. Schaack, Clayton K. Mickelson, Autumn E. Sanders, Tony Hu, Srishti Gupta, Ryan A. Langlois, Judith A. Smith, Andrew Mehle

2023Cell Host & Microbe52 citationsDOIOpen Access PDF

Topics & Concepts

BiologyInnate immune systemCas9DNAVirusExonucleaseCRISPRPathogenInfluenza A virusVirologyGeneDNA virusGenomeCell biologyGeneticsImmune systemDNA polymeraseinterferon and immune responsesCRISPR and Genetic EngineeringMosquito-borne diseases and control