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A Pd-Catalyzed Site-Controlled Isomerization of Terminal Olefins

Wenlong Ren, Fei Sun, Jianxiao Chu, Yian Shi

2020Organic Letters37 citationsDOI

Abstract

An effective Pd-catalyzed isomerization of olefins with 2-PyPPh2 as the ligand is described. A wide variety of trans-2-olefins bearing various functional groups can be obtained with high regio- and stereoselectivity under mild reaction conditions. The ligand is crucial for the reaction.

Topics & Concepts

IsomerizationChemistryStereoselectivityLigand (biochemistry)CatalysisTerminal (telecommunication)Olefin fiberReaction conditionsCombinatorial chemistryMedicinal chemistryStereochemistryOrganic chemistryReceptorBiochemistryTelecommunicationsComputer scienceSynthetic Organic Chemistry MethodsCatalytic Cross-Coupling ReactionsOrganometallic Complex Synthesis and Catalysis
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