Advances and Opportunities In Nanoimaging Agents for the Diagnosis of Inflammatory Lung Diseases
Hema Brindha Masanam, Govindaraj Perumal, Saravanan Krishnan, Sachin Kumar Singh, Niraj Kumar Jha, Dinesh Kumar Chellappan, Kamal Dua, Piyush Kumar Gupta, Ashwin Kumar Narasimhan
Abstract
The development of rapid, noninvasive diagnostics to detect lung diseases is a great need after the COVID-2019 outbreak. The nanotechnology-based approach has improved imaging and facilitates the early diagnosis of inflammatory lung diseases. The multifunctional properties of nanoprobes enable better spatial-temporal resolution and a high signal-to-noise ratio in imaging. Targeted nanoimaging agents have been used to bind specific tissues in inflammatory lungs for early-stage diagnosis. However, nanobased imaging approaches for inflammatory lung diseases are still in their infancy. This review provides a solution-focused approach to exploring medical imaging technologies and nanoprobes for the detection of inflammatory lung diseases. Prospects for the development of contrast agents for lung disease detection are also discussed.