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The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections

Jonathan Anomaly

2020Public Health Ethics53 citationsDOIOpen Access PDF

Abstract

For over a century, scientists have run experiments using phage viruses to treat bacterial infections. Until recently, the results were inconclusive because the mechanisms viruses use to attack bacteria were poorly understood. With the development of molecular biology, scientists now have a better sense of how phage work, and how they can be used to target infections. As resistance to traditional antibiotics continues to spread around the world, there is a moral imperative to facilitate research into phage therapy as an alternative treatment. This essay reviews ethical questions raised by phage therapy, and discusses regulatory challenges associated with phage research, and phage treatments.

Topics & Concepts

Phage therapyMicrobiologyBacteriophageVirologyBiologyGeneticsEscherichia coliGeneBacteriophages and microbial interactionsViral gastroenteritis research and epidemiologyPlant Virus Research Studies