The Many Facets of Hypermobile Ehlers-Danlos Syndrome
Bernadette Riley
Abstract
Of the 13 subtypes of Ehlers-Danlos Syndromes (EDSs) identified in the 2017 international classification of EDSs, 12 have a recognized, associated genetic mutation. However, hypermobile EDS (hEDS) currently has no identifiable associated gene. Therefore, patients with hEDS are identified through a set of clinical diagnosis guidelines and criteria, which are meant to differentiate hEDS from other hypermobile joint conditions and other EDSs subtypes. In this article, the authors provide an overview of hEDS symptoms and comborbidities, current treatment options, and the clinical criteria currently guiding the standard of care.
Topics & Concepts
MedicineEhlers–Danlos syndromeGene mutationIntensive care medicineMutationSurgeryGeneGeneticsBiologyConnective tissue disorders researchDermatological and Skeletal DisordersChild Abuse and Related Trauma