The left atrial appendage closure by surgery-2 (LAACS-2) trial protocol rationale and design of a randomized multicenter trial investigating if left atrial appendage closure prevents stroke in patients undergoing open-heart surgery irrespective of preoperative atrial fibrillation status and stroke risk

Christoffer Læssøe Madsen, Jesper Park-Hansen, Akhmadjon Irmukhamedov, Christian Lildal Carranza, Sulman Rafiq, Rafael Rodríguez-Lecoq, Neiser Palmer-Camino, Ivy Susanne Modrau, Emma C. Hansson, Anders Jeppsson, Rakin Hadad, Àngel Moya‐Mitjans, Anders M. Greve, Robin Christensen, Helle Gervig Carstensen, Nis Høst, Ulrik Dixen, Christian Torp‐Pedersen, Lars Køber, Ismail Gögenür, Thomas Truelsen, Christina Kruuse, Ahmad Sajadieh, Helena Domínguez