The safe Laccase@ZIF-8-prodrug system with GSH redox cycle for effective targeted cancer therapy with low off-target toxicity
Yu Zhou, Chengyu Zhang, Yuefei Wang, Jiaxing Zhang, Xiaohui Yan, Shengping You, Wei Qi, Rongxin Su, Zhimin He
Topics & Concepts
ProdrugChemistryGlutathioneToxicityReactive oxygen speciesCancer cellRedoxLaccaseAntioxidantBiochemistryEnzymePharmacologyCancerOrganic chemistryBiologyGeneticsNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryAdvanced Nanomaterials in Catalysis