Plasminogen activator Inhibitor-2 inhibits pulmonary arterial smooth muscle cell proliferation in pulmonary arterial hypertension via PI3K/Akt and ERK signaling
Shuai Zhang, Jing Wang, Xianmei Qi, Xincao Tao, Wanmu Xie, Jun Wan, Ying H. Shen, Zhenguo Zhai
Topics & Concepts
PI3K/AKT/mTOR pathwayPulmonary hypertensionRight ventricular hypertrophyPlasminogen activatorProtein kinase BInternal medicinePlasminogen activator inhibitor-1VentricleEndocrinologyActivator (genetics)BiologyPharmacologyMedicineSignal transductionCell biologyReceptorPulmonary Hypertension Research and TreatmentsProtease and Inhibitor MechanismsInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis