Polymersome-based protein drug delivery – quo vadis?
Micael G. Gouveia, Justus Paul Wesseler, Jobbe Ramaekers, Christoph Weder, Philip B. V. Scholten, Nico Bruns
Abstract
journey of polymersomes across various biological barriers. Considering this complex subject from a polymer chemist's point of view, we highlight key areas that are worthy to explore in order to advance polymersomes to a level at which clinical trials become worthwhile and translation into pharmaceutical and nanomedical applications is realistic.
Topics & Concepts
PolymersomeDrug deliveryDrugStatus quoNanotechnologyVesicleChemistryCopolymerPharmacologyAmphiphileMaterials scienceMedicineBiochemistryPolitical scienceMembraneOrganic chemistryLawPolymerNanoparticle-Based Drug DeliveryAdvanced Polymer Synthesis and CharacterizationRNA Interference and Gene Delivery