In Situ Biosynthesized Superparamagnetic Iron Oxide Nanoparticles (SPIONS) Induce Efficient Hyperthermia in Cancer Cells
Swati Kaushik, Jijo Thomas, Vineeta Panwar, Hasan Ali, Vianni Chopra, Anjana Sharma, Ruchi Tomar, Deepa Ghosh
Abstract
) and the involvement of the glycolytic pathway in the biosynthesis of the nanoparticles were confirmed using appropriate in vitro studies. The simplicity of treatment, the specificity of cells capable of synthesis of SPIONS, and the hyperthermia response observed in cancer cells indicate a promising strategy to achieve effective magnetic hyperthermia for cancer therapy.
Topics & Concepts
Iron oxide nanoparticlesHyperthermiaMagnetic hyperthermiaNanoparticleCancer cellSuperparamagnetismCancerMagnetic nanoparticlesNanotechnologyIron oxideChemistryMagnetiteMaterials scienceBiophysicsCancer researchMedicineBiologyMagnetic fieldMagnetizationInternal medicineOrganic chemistryMetallurgyQuantum mechanicsPhysicsNanoparticle-Based Drug DeliveryUltrasound and Hyperthermia ApplicationsRadiation Therapy and Dosimetry