Induction of monoamine oxidase A-mediated oxidative stress and impairment of NRF2-antioxidant defence response by polyphenol-rich fraction of Bergenia ligulata sensitizes prostate cancer cells in vitro and in vivo
Suvranil Ghosh, Naibedya Dutta, Pinaki P. Banerjee, Rahul L. Gajbhiye, HOSSAINOOR RAHAMAN SARENG, Prachi Kapse, Srabani Pal, Lyudmila G. Burdelya, Narayan Chandra Mandal, V. Ravichandiran, Ashish Bhattacharjee, Gopal C. Kundu, Andrei V. Gudkov, Mahadeb Pal
Topics & Concepts
LNCaPOxidative stressChemistryProgrammed cell deathApoptosisPharmacologyDU145Protein kinase BMonoamine oxidaseReactive oxygen speciesClonogenic assayIn vivoProstate cancerCancer researchCancerMedicineBiochemistryBiologyInternal medicineEnzymeBiotechnologyGenomics, phytochemicals, and oxidative stressPlant-derived Lignans Synthesis and BioactivityPhytochemistry and Bioactivity Studies