Guidance on use of race, ethnicity, and geographic origin as proxies for genetic ancestry groups in biomedical publications
W Feero, Robert D. Steiner, Anne Slavotinek, Tiago Faial, Michael J. Bamshad, Jehannine Austin, Bruce R. Korf, Annette Flanagin, Kirsten Bibbins‐Domingo
Abstract
In March 2023, the National Academies of Sciences, Engineering, and Medicine (NASEM) released a consensus study report titled Using Population Descriptors in Genetics and Genomics Research.1 Sponsored by the US National Institutes of Health, the report is more than a discussion of the use of terminology; the authors of the NASEM report suggest a tectonic shift away from current models that use race, ethnicity, and geographic origin as proxies for genetic ancestry groups (i.e., a set of individuals who share more similar genetic ancestries) in genetic and genomic science.
Topics & Concepts
Race (biology)Ethnic groupGenetic genealogyDemographyGeographyMedicineBiologyAnthropologySociologyPopulationBotanyBRCA gene mutations in cancerRace, Genetics, and SocietyEthics in Clinical Research