Breast cancer diagnosis based on lipid profiling by probe electrospray ionization mass spectrometry
Tomohiko Iwano, Kenichi Yoshimura, Shunsuke Inoue, Toru Odate, Koretsugu Ogata, Shinji Funatsu, Hiroshi Tanihata, Tetsuo Kondo, Daisuke Ichikawa, Sén Takeda
Abstract
Probe electrospray ionization mass spectrometry (PESI-MS) is an ambient ionization-based mass spectrometry method that surpasses the original electrospray ionization technique in features such as the rapidity of analysis, simplicity of the equipment and procedure, and lower cost. This study found that the PESI-MS system with machine learning has the potential to establish a lipid-based diagnosis of breast cancer with higher accuracy, using a simpler approach. Rapid mass spectrometry for breast cancer.
Topics & Concepts
MedicineMass spectrometryProfiling (computer programming)Breast cancerElectrospray ionizationChromatographyCancerInternal medicineChemistryComputer scienceOperating systemMass Spectrometry Techniques and ApplicationsMetabolomics and Mass Spectrometry StudiesAnalytical Chemistry and Chromatography