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Design and synthesis of novel tetrazolo quinoline bridged isatin derivatives as potential anticancer leads against MIA PaCa-2 human pancreatic cancer cell line

B. N. Nippu, Sandeep Kumar Jain R, Abdul Rahman, H．M． Kumaraswamy, Nayak Devappa Satyanarayan

2022Journal of Molecular Structure14 citationsDOI

Topics & Concepts

ChemistryIn silicoIsatinDocking (animal)QuinolineStereochemistryIn vitroCombinatorial chemistryProtein Data Bank (RCSB PDB)Pancreatic cancerMoleculeIC50BiochemistryCancerOrganic chemistryInternal medicineNursingMedicineGeneComputational Drug Discovery MethodsSynthesis and biological activitySynthesis of Tetrazole Derivatives
Design and synthesis of novel tetrazolo quinoline bridged isatin derivatives as potential anticancer leads against MIA PaCa-2 human pancreatic cancer cell line | Litcius