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Methoxyeugenol deactivates hepatic stellate cells and attenuates liver fibrosis and inflammation through a PPAR-ɣ and NF-kB mechanism

Bruno de Souza Basso, Gabriela Viegas Haute, Martí Ortega‐Ribera, Carolina Luft, Géssica Luana Antunes, Matheus Scherer Bastos, Leonardo Pfeiff Carlessi, Vitor Giancarlo Schneider Levorse, Eduardo Cassel, Márcio Vinı́cius Fagundes Donadio, Eliane Romanato Santarém, Jordi Gracia‐Sancho, Jarbas Rodrigues de Oliveira

2021Journal of Ethnopharmacology64 citationsDOIOpen Access PDF

Topics & Concepts

Hepatic stellate cellFibrosisHepatocytePharmacologyHepatic fibrosisCancer researchLiver functionLiver diseaseIn vivoLiver injuryChronic liver diseaseInflammationMedicinePeroxisome proliferator-activated receptorBiologyImmunologyPathologyInternal medicineReceptorCirrhosisIn vitroBiochemistryBiotechnologyLiver physiology and pathologyPlant-derived Lignans Synthesis and BioactivityDrug-Induced Hepatotoxicity and Protection
Methoxyeugenol deactivates hepatic stellate cells and attenuates liver fibrosis and inflammation through a PPAR-ɣ and NF-kB mechanism | Litcius