Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial
Mazen Noureddin, Juan P. Frías, Guy Neff, K. Lucas, Cynthia Behling, Pierre Bédossa, Julie Dubourg, Doreen Chan, Mark Burch, Erica Fong, Brittany de Temple, Matt Minerva, Kim E. Barrett, Reshma Shringarpure, Erik J. Tillman, Tim Rolph, Andrew Cheng, Kitty Yale
Topics & Concepts
MedicineSteatohepatitisPlaceboClinical endpointInternal medicineFatty liverSurrogate endpointGastroenterologyIntention-to-treat analysisSteatosisAdverse effectRandomized controlled trialSurgeryDiseasePathologyAlternative medicineLiver Disease Diagnosis and TreatmentFibroblast Growth Factor ResearchLiver physiology and pathology