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A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers

Stephanie Guerra, Ophélia Maertens, Ryan Kuzmickas, Thomas De Raedt, Richard O. Adeyemi, Caroline J. Guild, Shawna Guillemette, Amanda J. Redig, Emily S. Chambers, Man Xu, Hong L. Tiv, Sandro Santagata, Pasi A. Jänne, Stephen J. Elledge, Karen Cichowski

2020Cancer Cell56 citationsDOIOpen Access PDF

Topics & Concepts

KRASBiologyEpigeneticsCancer researchMutantHox geneMutationGeneHomeoboxGeneticsGene expressionProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors Research
A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers | Litcius