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Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein–host ACE2 binding

Luke Invernizzi, Phanankosi Moyo, Joel Cassel, Freddie J. Isaacs, Joseph M. Salvino, Luis J. Montaner, Ian Tietjen, Vinesh Maharaj

2022Analytical and Bioanalytical Chemistry24 citationsDOIOpen Access PDF

Topics & Concepts

IC50GlycoproteinChemistryPharmacologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Viral entryCoronavirus disease 2019 (COVID-19)BiochemistryTraditional medicineBiologyVirologyVirusMedicineViral replicationInfectious disease (medical specialty)DiseaseIn vitroPathologyEssential Oils and Antimicrobial ActivityPiperaceae Chemical and Biological StudiesPhytochemicals and Medicinal Plants
Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein–host ACE2 binding | Litcius