Cell cycle and developmental control of cortical excitability in <i>Xenopus laevis</i>
Zachary T. Swider, Ani Michaud, Marcin Leda, Jennifer Landino, Andrew B. Goryachev, William M. Bement
Abstract
eggs and embryos and the changes in cortical excitability throughout early development. We found that cortical excitability begins to manifest shortly after egg activation. Further, we identified a close relationship between wave properties-such as wave frequency and amplitude-and cell cycle progression as well as cell size. Finally, we identified quantitative differences between cortical excitability in the cleavage furrow relative to nonfurrow cortical excitability and showed that these wave regimes are mutually exclusive.
Topics & Concepts
BiologyXenopusCell biologyCell cycleNeuroscienceCellGeneticsGeneNeural dynamics and brain functionstochastic dynamics and bifurcationPhysiological and biochemical adaptations