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Evaluation of anticancer role of a novel ruthenium(II)-based compound compared with NAMI-A and cisplatin in impairing mitochondrial functionality and promoting oxidative stress in triple negative breast cancer models

Sonia Silvestri, Ilenia Cirilli, Fabio Marcheggiani, Phiwayinkosi V. Dludla, Giulio Lupidi, Riccardo Pettinari, F. Marchetti, Corrado Di Nicola, Giancarlo Falcioni, Cristina Marchini, Patrick Orlando, Luca Tiano, Augusto Amici

2020Mitochondrion31 citationsDOI

Topics & Concepts

Oxidative stressCisplatinChemistryMitochondrionTriple-negative breast cancerRespiratory chainPharmacologyReactive oxygen speciesToxicityMitochondrial respiratory chainBiochemistryCancerCancer researchBiophysicsBiologyBreast cancerMedicineChemotherapyInternal medicineOrganic chemistryMetal complexes synthesis and propertiesLanthanide and Transition Metal ComplexesFerrocene Chemistry and Applications
Evaluation of anticancer role of a novel ruthenium(II)-based compound compared with NAMI-A and cisplatin in impairing mitochondrial functionality and promoting oxidative stress in triple negative breast cancer models | Litcius