Molecular regulation of autophagy and suppression of protein kinases by aescin, a triterpenoid saponin impedes lung cancer progression
Jyoti Singh, Yusuf Hussain, Abha Meena, Suaib Luqman, Rohit A. Sinha
Topics & Concepts
KinasePI3K/AKT/mTOR pathwayAutophagyLung cancerProtein kinase BCancer researchCancerMAPK/ERK pathwayBiologyPharmacologyChemistryPhosphorylationCell biologyBiochemistrySignal transductionApoptosisMedicineInternal medicineGeneticsAutophagy in Disease and TherapyPlant biochemistry and biosynthesisNatural product bioactivities and synthesis