Rational design of polymer-based mRNA delivery systems for cancer treatment
Qianyu Wan, Yuji Sun, Xuanrong Sun, Zhuxian Zhou
Abstract
This review introduces the basic design principles and recent advances in polymeric mRNA therapeutics, highlighting strategies to realize cancer-selective, organ-targeted, and tissue-penetrating mRNA delivery.
Topics & Concepts
Rational designPolymerMessenger RNAChemistryNanotechnologyMaterials scienceBiochemistryOrganic chemistryGeneRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesNanoparticle-Based Drug Delivery