ΔNp63α mediates sulforaphane suppressed colorectal cancer stem cell properties through transcriptional regulation of Nanog/Oct4/Sox2
Yue Chen, Meng-Huan Wang, Jin‐Yi Wu, Jianyun Zhu, Chunfeng Xie, Xiaoting Li, Jieshu Wu, Shanshan Geng, Yadong Li, Hongyu Han, Caiyun Zhong
Topics & Concepts
Homeobox protein NANOGSOX2SulforaphaneCancer stem cellColorectal cancerCancer researchCD44KLF4Downregulation and upregulationMetastasisTranscription factorStem cellChemistryBiologyCancerCellCell biologyEmbryonic stem cellInduced pluripotent stem cellGeneticsBiochemistryGeneGenomics, phytochemicals, and oxidative stressMicroRNA in disease regulationRNA modifications and cancer