Exogenous ketosis attenuates acute mountain sickness and mitigates normobaric high-altitude hypoxemia
Myrthe Stalmans, Domen Tominec, Wout Lauriks, Ruben Robberechts, Tadej Debevec, Chiel Poffé
Abstract
Ketone ester intake attenuated the development of acute mountain sickness at a simulated altitude of 4,000-4,500 m. This likely resulted from a mitigation of arterial and cerebral hypoxemia, reduced cerebral blood flow, and increased sympathetic drive.
Topics & Concepts
HypoxemiaMedicineAcidosisHypoxia (environmental)HyperventilationOxygenationAltitude sicknessEffects of high altitude on humansCerebral blood flowAnesthesiaKetosisMetabolic acidosisInternal medicineEndocrinologyOxygenChemistryDiabetes mellitusAnatomyOrganic chemistryHigh Altitude and HypoxiaNeuroscience of respiration and sleepAdipose Tissue and Metabolism