Multicenter Evaluation of the Unyvero Platform for Testing Bronchoalveolar Lavage Fluid
Matthias Klein, Johannes Bacher, Sandra Barth, Faranak Atrzadeh, Katja Siebenhaller, Inês M. Ferreira, Stephan Beisken, Andreas E. Posch, Karen C. Carroll, Richard G. Wunderink, Chao Qi, Fann Wu, Dwight J. Hardy, Robin Patel, Matthew Sims
Abstract
Bronchoalveolar lavage (BAL) culture is a standard, though time-consuming, approach for identifying microorganisms in patients with severe lower respiratory tract infections. The sensitivity of BAL culture is relatively low, and prior antimicrobial therapy decreases the sensitivity further, leading to overuse of empirical antibiotics.
Topics & Concepts
Bronchoalveolar lavagePneumocystis jiroveciiAntibioticsAntibiotic resistanceMicrobiologyMedicinePneumoniaMultiplex polymerase chain reactionMicrobiological cultureInternal medicineImmunologyBacteriaBiologyLungPolymerase chain reactionGeneticsGeneBiochemistryPneumonia and Respiratory InfectionsRespiratory viral infections researchAntifungal resistance and susceptibility