Immunostimulatory effects of thermal ablation: Challenges and future prospects
Peng Liu, Zhigang Wei, Xin Ye
Abstract
ABSTRACT: This literature explores the immunostimulatory effects of thermal ablation in the tumor microenvironment, elucidating the mechanisms such as immunogenic cell death, tumor-specific antigens, and damage-associated molecular patterns. Furthermore, it outlines critical issues associated with thermal ablation-induced immunostimulatory challenges and offers insights into future research avenues and potential therapeutic strategies.
Topics & Concepts
Thermal ablationTumor microenvironmentAblationTumor ablationComputational biologyImmune systemBiologyMedicineImmunologyInternal medicineCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCAR-T cell therapy research