Transcriptomic analysis in zebrafish larvae identifies iron-dependent mitochondrial dysfunction as a possible key event of NAFLD progression induced by benzo[a]pyrene/ethanol co-exposure
Muhammad Imran, Frédéric Chalmel, Odile Sergent, Bertrand Evrard, Hélène Le Mentec, Antoine Legrand, Aurélien Dupont, Maëlle Bescher, Simon Bucher, Bernard Fromenty, Laurence Huc, Lydie Sparfel, Dominique Lagadic‐Gossmann, Normand Podechard
Topics & Concepts
Oxidative stressSteatohepatitisAryl hydrocarbon receptorSteatosisMitochondrionFatty liverBenzo(a)pyreneBiologyChemistryZebrafishTranscriptomePharmacologyBiochemistryCarcinogenCell biologyInternal medicineEndocrinologyMedicineGeneGene expressionTranscription factorDiseaseLiver Disease Diagnosis and TreatmentAlcohol Consumption and Health EffectsMetabolomics and Mass Spectrometry Studies