Vitamin D<sub>3</sub>attenuates cisplatin-induced intestinal injury by inhibiting ferroptosis, oxidative stress, and ROS-mediated excessive mitochondrial fission
Xingyao Liu, Shuang Wang, Shengzi Jin, Siqi Huang, Yun Liu
Abstract
protected against CP-induced intestinal injury by inhibiting ferroptosis and alleviating oxidative stress and ROS-mediated excessive mitochondrial fission, suggesting that it may be a novel and promising candidate to prevent CP-induced intestinal injury.
Topics & Concepts
Oxidative stressAntioxidantReactive oxygen speciesChemistryVitaminMitochondrionOxidative phosphorylationCell biologyPharmacologyBiochemistryBiologyFerroptosis and cancer prognosisTrace Elements in HealthDrug Transport and Resistance Mechanisms