Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases
Hyewon Jang, Dong Hyun Jo, Chang Sik Cho, Jeong Hong Shin, Jung Hwa Seo, Goosang Yu, Ramu Gopalappa, Daesik Kim, Sung‐Rae Cho, Jeong Hun Kim, Seokjoong Kim
Topics & Concepts
PhenotypeBiologyGenome editingGeneticsGeneMutationPrime (order theory)Vector (molecular biology)RNAComputational biologyCRISPRRecombinant DNACombinatoricsMathematicsCRISPR and Genetic EngineeringRNA regulation and diseaseRetinal Development and Disorders